Figure 4

Urine JM403 values corrected for urine creatinine concentration on samples collected on indicated days from the study patients. Individual values are shown to appreciate the differences between patients. Values are expressed as Units/mg creatinine. One unit is defined as the amount of JM403 epitope present on 1 microgram kidney heparan sulfate. Sample on Day 9 of patient X is missing because he forgot to collect the sample. The top line of asterixes represents data from a patient that also had stable chronic pancreatitis, a condition not known to be associated with type Z alpha-1-antitrypsin deficiency. The other patient with normal values had no other known conditions and had a stable lung function for the past 15 years as measured in our clinic.