Respiratory Research

Table 3 Spearman's rank correlations between current smoking and airway obstruction and airway inflammation.

From: Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers

	COPD GOLD I-III (n = 19)		Asymptomatic smokers (n = 26)
	rho	p-value	rho	p-value
Cigarettes/day
Neutrophils sputum, %	-0.46	0.02	-0.24	NS
Macrophages sputum, %	0.44	0.027	0.35	0.095
Eosinophils sputum, %	-0.19	NS	-0.39	0.057
Eosinophils sputum, 10⁶/ml	-0.11	NS	-0.44	0.029
CD68 biopsy, % pos. area	0.69	0.002	0.46	0.029
EG2 biopsy, % pos. area	-0.79	0.001	0.02	NS
Pack-years smoking
CD68 biopsy, %pos. area	0.48	0.043	0.21	NS
FEV₁post BD, %pred.
Neutrophils sputum, %	-0.31	NS	0.15	NS
Macrophages sputum, %	0.41	0.046	-0.22	NS
IL-8 sputum, ng/ml	-0.54	0.007	0.15	NS
CD68 biopsy, %pos. area	0.33	NS	0.18	NS
AA1 biopsy, %pos. area	0.53	0.02	0.09	NS

CD68 = macrophages; EG2 = eosinophils; % pos. area = percentage positive area; FEV1 = forced expiratory volume in one second; post BD = post bronchodilator (15 minutes after 400 μg salbutamol); IL-8 = interleukin 8; AA1 = mast cells; NS = not significant

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ISSN: 1465-993X

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