Figure 3
From: Titanium dioxide particle – induced goblet cell hyperplasia : association with mast cells and IL-13
The cell distribution in BAL fluid of TiO2 instilled rats with or without pretreatment. Rats were pretreated with CPA (n = 6) or DEX (n = 6) and then treated intratracheally with TiO2. Saline (n = 8) or TiO2 (n = 8) was treated without pretreatment. At 48 h post-treatment, BAL fluids were collected and analyzed for the numbers of eosinophils (A), neutrophils(B), and the levels of IL-13(D). PAS (+) cells (C) were measured in the trachea as described in Methods. * p < 0.05 as compared with saline – treated group, † p < 0.05 as compared with TiO2 – treated group.