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Figure 4 | Respiratory Research

Figure 4

From: Airway allergen exposure stimulates bone marrow eosinophilia partly via IL-9

Figure 4

Effect of treatment with the neutralizing antibodies on allergen-induced changes of BAL granulocytes stained for CD34 in Balb/c mice (sensitized and on five days exposed to OVA). Animals were pretreated with a) anti-IL-9 antibody or its isotype control IgG (100 μg/animal); or with b) anti-IL-5 antibody or its isotype control IgG1 (50 μg/animal) 30 minutes before the first exposure. Data are shown as mean ± SEM (n = 5–10 per group). **p < 0.01 compared with the corresponding isotype control antibody (Mann-Whitney U test).

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