Skip to main content

Table 1 Ventilatory parameters at baseline (90% O2) before hyperoxia, after hyperoxia and during recovery.

From: Deficiency in type 1 insulin-like growth factor receptor in mice protects against oxygen-induced lung injury

 

IGF-1R+/+

IGF-1Rneo/-

 

Before hyperoxia

After hyperoxia

During recovery

Before hyperoxia

After hyperoxia

During recovery

VE

2.03 ± 0.17

2.35 ± 0.32 #

2.84 ± 0.69#

2.27 ± 0.22 *

2.93 ± 0.37 *#

3.30 ± 0.62#

VT

10.0 ± 0.5

15.8 ± 2.0#

14.4 ± 2.2#

11.2 ± 0.8 *

15.2 ± 1.1#

14.8 ± 1.1#

fR

203 ± 9

142 ± 30#

196 ± 32

203 ± 21

192 ± 18 *#

222 ± 35

  1. Values are mean parameters ± SD in IGF-1R+/+ mice (n = 6) and IGF-1Rneo/- mice (n = 5) mice; VE, minute ventilation expressed in ml/min/g, VT, tidal volume in μl/g, fR, respiratory frequency in c/min; # significant difference relative to control before hyperoxia; * significant difference between the two genotypes (P < 0.05).