Figure 5
From: Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling
The effect of ovalbumin sensitisation and challenge on airway sub-epithelial proteoglycan and decorin deposition. Cupromeronic Blue staining of representative airways from (A) control and (B) ovalbumin sensitised/challenged airways 12 days after final challenge. The reticular pattern of staining is seen particularly around the airway circumference in a distribution corresponding to the sub-epithelial layer. Staining is greater in ovalbumin sensitised/challenged airways. Decorin immunostaining of representative airways from (C) control and (D) ovalbumin sensitised/challenged airways at the same time point. Immunostaining is concentrated in the walls of airways and vessels and is not seen in the lung parenchyma. Immunostaining is greater in ovalbumin sensitised/challenged airways and vessels. Scale bars represent 50 μm.