Figure 3

Effect of atorvastatin on LPS-induced expression of COX-2 protein. A549 cells were treated as described in Figure 2. After incubation, the cells were harvested, and sonicated. COX-2 protein in the cell lysates was detected by Western-blot using a specific antibody against COX-2. A representative western-blot gel. (top) and the density of COX-2 band (bottom) are shown. * P = 0.001 vs non atorvastatin; P < 0.05 vs 10 μM atorvastatin; ^• P < 0.05 vs 15 μM atorvastatin group.