Figure 2

Effect of atorvastatin on LPS-induced expression of COX-2 mRNA. A549 cells were treated with various concentrations of atorvastatin in the presence of LPS (10 μg/ml) for 9 h. After incubation, total RNA were extracted and assayed by RT-PCR. A representative gel. (top) and relative density of gel. (bottom) are shown. * P <0.05 vs non- atorvastatin. P < 0.05 10 μM vs atorvastatin group; ^• P < 0.05 vs 15 μM atorvastatin group.