Figure 1
A: Dose-dependent effect of LPS on COX-2 mRNA expression. A549 cells were incubated with various concentrations of LPS for 9 h (top, * P < 0.05 vs LPS 5 μg/ml). B: Time-dependent effect of LPS on COX-2 mRNA expression. A549 cells were incubated with LPS (10 μg/ml) for various times (middle, * P < 0.05 vs 6 hrs group;). C: Time- and dose-dependent effects of LPS on PGE2 production (bottom, * P < 0.05 vs non-LPS group; • P < 0.05 vs 5 μg/ml LPS group; # P < 0.01 vs non-LPS group; 
P < 0.05 vs 6 h group). These data were representative of three separate experiments.