Table 1 Ventilatory parameters, lung mechanics and arterial blood gases at inhibition of spontaneous breathing

PIP (kPa)

1.3 ± 0.2

2.8 ± 0.6*

2.9 ± 0.6*

*<0.001

P _tp (kPa)

0.98 ± 0.2

2.36 ± 0.7 *

2.46 ± 0.6*

*<0.001

V _t (ml/kg)

10 ± 1.2

17 ± 2.6*

19 ± 5.6*

*<0.02

C _L (ml/kPa)

41.5 [34;47]

18 [16;25]*

17 [14;20]*

*<0.05

Resistance (kPa/L/s)

2.58 ± 0.59

4.94 ± 0.54*

5.49 ± 0.59 *‡

*<0.001

‡ = 0.038

pH

7.42 ± 0.05

7.38 ± 0.07

7.33 ± 0.8*

* = 0.008

PaCO ₂ , kPa

5.5 ± 0.9

5.2 ± 0.6

6.3 ± 1.7‡

‡ = 0.027

PaO ₂ , kPa

14.1 ± 1.8

11.0 ± 6.0

29.2 ± 17.1*‡

* = 0.01

‡ = 0.01

BE

1.71 ± 1.47

-2.08 ± 2.97*

-1.89 ± 3.95*

*<0.001