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Table 2 Expression of CXCR3 by CD8+ T cells and expression of IP-10/CXCL10 and Mig/CXCL9 mRNAs by alveolar macrophages from patients with hypersensitivity pneumonitis and controls*

From: CXCR3/CXCL10 interactions in the development of hypersensitivity pneumonitis

Study population

CXCR3+/CD8+ T cells

IP-10/CXCL10

Mig/CXCL9

 

%

cells × 103/ml

mRNA levels*

mRNA levels

HP (n. 6)

51.7** ± 5.9

80.1*** ± 7.7

2.55** ± 0.14

2.25** ± 0.25

Controls (n. 4)

23.7 ± 2.2

2.5 ± 0.3

0.70 ± 0.05

0.48 ± 0.06

  1. * Band intensity calculated as follows: mm × mm × pixel Significance as follows: **p < 0.01; ***p < 0.001