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Table 2 Total and differential leukocyte cell counts in COPD sputum sampled prior to and during exacerbation† (n = 12)

From: MMP-9, TIMP-1 and inflammatory cells in sputum from COPD patients during exacerbation

Cell type Pre-exacerbation Exacerbation P-value
  Median IQR Median IQR  
Total cell (106 cells/g) 1.61 0.88–2.25 2.86 1.64–7.2 <0.01
% viability 65.14 56.05–74.92 83.33 65.57–88.60 <0.01
Neutrophil (106 cells/g) 1.48 0.84–2.02 2.19 1.10–6.16 <0.05
% Neutrophils 80.0 72.63–89.30 87.5 78.38–89.25 NS
Macrophage (106 cells/g) 0.23 0.13–0.25 0.26 0.15–0.42 NS
% Macrophages 17.25 6.63–22.25 6.0 5.38–17.5 <0.05
Eosinophil (106 cells/g) 0.01 0.002–0.03 0.07 0.02–0.10 <0.01
% Eosinophils 0.75 0.25–1.38 1.0 0.63–3.00 NS
Lymphocyte (106 cells/g) 0.03 0.02–0.07 0.13 0.05–0.3 <0.05
% Lymphocytes 2.50 1.38–4.38 4.5 1.25–5.63 NS
  1. † Paired sputa from 12 individuals.