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Table 5 Qualitative stratification of clinical disorders and positive allergy skin tests by serum IgE (geometric mean, 95% C.I.).

From: Pathophysiological classification of chronic rhinosinusitis

 

IgE < 10 IU/ml

10 ≤ IgE ≤ 100 IU/ml

IgE > 100 IU/ml

IgE

1.7 (0.8 to 2.9)

35.1 (28.1 to 43.7)

277 (212 to 364)

Clinical Asthma B

14/29 (48%)

23/28 (82%) [0.005]

24/29 (83%) [0.005]

FEV1/FVC ≤ 70%

5/17 (29%)

7/18 (39%)

10/18 (56%)

FEF25%–75% ≤ 70%

7/17 (41%)

11/17 (65%)

12/18 (67%)

Nasal Polyps

9/29 (31%)

15/28 (54%)

17/29 (59%) [0.02]

Eosinophilia > 4%

8/28 (29%)

12/28 (43%)

16/29 (55%) [0.03]

Positive Allergy Skin Test Results

N per group

28

26

26

+ Results/subject †

0.74 (0.10 to 1.30)

3.5 (1.82 to 5.43) †

5.08 (3.90 to 6.27) ††

Trees C

3 (11%)

6 (23%) {0.01}

15 (58%) [0.0003]

Grasses A

4 (14%)

8 (31%)

12 (46%) [0.009]

Weeds

2 (7%)

7 (27%) [0.047]

4 (15%)

Ragweed C

0 (0%)

8 (31%) [0.002]

12 (46%) [0.00003]

Fungi B

1 (4%)

5 (19%) {0.049}

11 (42%) [0.0006]

Cat B

3 (11%)

7 (27%)

13 (50%) [0.0002]

D. farinae D

1 (4%)

12 (46%) [0.0002]

18 (69%) [10-6]

D. pteronyssinus D

2 (7%)

10 (39%) [0.006] {0.03}

17 (65%) [10-5]

"Persistent" §D

4 (14%)

15 (58%) [0.001] {0.01}

23 (88%) [10-8]

  1. ANOVA: A = 0.04; B = 0.004; C = 0.0003; D < 0.00003. [p] = Fisher's Exact test vs. IgE<10 IU/ml; {p} vs. IgE>100 IU/ml. † Number of positive allergy skin test results per subject (mean; 95% CI): † p = 0.003 and †† p = 10-7 vs. IgE<10 IU/ml by 2-tailed, unpaired Student's t-test.