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Table 3 Results of 2-SNP haplotype analyses in the Hutterites. In this sample, IL13_+1923C/T is in perfect LD (r2 = 1) with IL13_Arg130Gln (G→ A); SNP2 C/T is in perfect LD with IL4_-589C/T, SNP4G/A, and IL4_+8374A/G; IL4_+3017G/T is in perfect LD with SNP7A/G and SNP8C/G (Table 2). Only haplotypes and phenotypes with at least one P-value < 0.05 are shown. The number of cases in each analysis is shown in parentheses. P-values that were significant after adjusting for multiple comparisons are in bold font.

From: Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy

  

Specific IgE Response (+SPT) to

Locus 1

Locus 2

Mold (N = 75)

Cockroach (N = 148)

IL13_--1112

IL13_+1923

0.0063

0.042

 

SNP2

0.00020

0.0022

 

IL4_+3017

0.033

0.0074

IL13_+1923

SNP2

0.00033

0.0017

 

IL4_+3017

0.017

0.042