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Table 2 Clinical classification based on GINA guidelines of all asthmatics, including those who returned a positive challenge

From: The safety and efficacy of inhaled dry powder mannitol as a bronchial provocation test for airway hyperresponsiveness: a phase 3 comparison study with hypertonic (4.5%) saline

ADULTS

Mild

Moderate

Severe

n (Total)

191

151

36

n (with PD15)

80

107

35

GeoMean PD15 mg (95% CI)

186 (148, 233)

78* (58, 106)

56* (36, 98)

CHILDREN

Infrequent Episodic

Frequent Episodic

Persistent

n (Total)

24

19

66

n (with PD15)

18

14

54

GeoMean PD15 mg (95% CI)

113 (59, 217)

117 (73, 187)

67 (46, 99)

  1. * p < 0.001 compared with mild