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Table 2 Clinical classification based on GINA guidelines of all asthmatics, including those who returned a positive challenge

From: The safety and efficacy of inhaled dry powder mannitol as a bronchial provocation test for airway hyperresponsiveness: a phase 3 comparison study with hypertonic (4.5%) saline

ADULTS Mild Moderate Severe
n (Total) 191 151 36
n (with PD15) 80 107 35
GeoMean PD15 mg (95% CI) 186 (148, 233) 78* (58, 106) 56* (36, 98)
CHILDREN Infrequent Episodic Frequent Episodic Persistent
n (Total) 24 19 66
n (with PD15) 18 14 54
GeoMean PD15 mg (95% CI) 113 (59, 217) 117 (73, 187) 67 (46, 99)
  1. * p < 0.001 compared with mild