Figure 7
Effect of RB2 and α-β-methylene ATP on rat airway rings. A: Fmax to 10-3 M ATP in rat airway rings (n = 8) and human IPB (HumIPB, n = 8) in the presence of 10 μM RB2. B: Fmax to 10-4 M α-β-methylene ATP in rat airway rings (N = 7 to 8). Horizontal bars are Fmax in control conditions. C: TR10 in rat airway rings stimulated with 10-4 M α-β-methylene ATP. Vertical bars are TR10 in control conditions, i.e., 10-4 M ATP. Trachea: black column; left (LEPB) and right EPB (REPB): hatched columns; left IPB: cross-hatched column. Error bars are SEM. *P < 0.05.