|
% BrdU positive nucleia
|
---|
Stimuli
|
BrdU incubation period
|
---|
|
24–48 h
|
48–72 h
|
---|
|
wound
|
intact
|
wound
|
intact
|
---|
Medium
|
21.5 ± 0.7
|
17.0 ± 1.6
|
20.9 ± 1.0
|
12.4 ± 1.4
|
TGFα
|
47.3 ± 3.9*
|
34.9 ± 1.5*
|
27.5 ± 0.5*
|
16.4 ± 2.2
|
NAC
|
22.5 ± 2.9
|
16.3 ± 1.8
|
20.5 ± 1.1
|
14.4 ± 1.3
|
CSC 1 AU/ml
|
39.8 ± 1.0*
|
29.5 ± 3.8*
|
42.2 ± 1.6*
|
24.0 ± 2.3
|
CSC 1 AU/ml+NAC
|
25.7 ± 0.7ˆ
|
17.4 ± 2.7ˆ
|
21.8 ± 2.5ˆ
|
16.0 ± 1.8ˆ
|
- aPercentage BrdU-positive nuclei within a distance of 10 cells from the wound edge (i.e. within the original wound area) and in intact areas. Data are mean ± SEM of 3 independent experiments. *: p < 0.05 versus serum-free medium-treated cells. ˆ:p < 0.05 vs CSC 1 AU/ml