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Table 1 Cell proliferation in mechanically wounded NCI-H292 cell monolayers: effect of CSC.

From: Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione

  % BrdU positive nucleia
Stimuli BrdU incubation period
  24–48 h 48–72 h
  wound intact wound intact
Medium 21.5 ± 0.7 17.0 ± 1.6 20.9 ± 1.0 12.4 ± 1.4
TGFα 47.3 ± 3.9* 34.9 ± 1.5* 27.5 ± 0.5* 16.4 ± 2.2
NAC 22.5 ± 2.9 16.3 ± 1.8 20.5 ± 1.1 14.4 ± 1.3
CSC 1 AU/ml 39.8 ± 1.0* 29.5 ± 3.8* 42.2 ± 1.6* 24.0 ± 2.3
CSC 1 AU/ml+NAC 25.7 ± 0.7ˆ 17.4 ± 2.7ˆ 21.8 ± 2.5ˆ 16.0 ± 1.8ˆ
  1. aPercentage BrdU-positive nuclei within a distance of 10 cells from the wound edge (i.e. within the original wound area) and in intact areas. Data are mean ± SEM of 3 independent experiments. *: p < 0.05 versus serum-free medium-treated cells. ˆ:p < 0.05 vs CSC 1 AU/ml