Figure 5

Intracellular GSH in NCI-H292 after exposure to CSC. NCI-H292 cells were exposed to various concentrations of CSC (5, 2.5 and 1.25 AU/ml) in presence or absence of NAC (1 mM), or NAC alone for 1 (open bars), 3 (hatched bars) or 5 h (filled bars). Intracellular GSH content was measured in cellular lysates and expressed as mean percentage ± SEM of that of medium-treated cells. p < 0.05 vs medium-treated cells; GSH content of cells exposed to 5 AU/ml CSC alone or with NAC differed significantly at 3 h (P = 0.04).