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Figure 2 | Respiratory Research

Figure 2

From: Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione

Figure 2

Effect of CSC on epithelial wound closure in NCI-H292 cells and PBEC. Mechanical wounds were prepared in monolayers of NCI-H292 (panel A) or PBEC (panel B) and the area of the wound was determined at various time points as indicated and used to calculate the % wound closure. Following wounding, the cultures were incubated with freshly prepared CSC (5 or 1 AU/ml; ■, ), TGF-α (; 20 ng/ml) or medium alone (). The results in panel A (NCI-H292 cells) are mean ± SEM of 6 independent experiments, each performed in triplicate. The results in panel B (PBEC) are mean ± SEM of PBEC cultures derived from 7 different donors. ** P < 0.004; * P < 0.05 vs medium alone

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