Figure 4
From: Marked alveolar apoptosis/proliferation imbalance in end-stage emphysema
Smoking-related emphysema case 3: a) double labeling TUNEL/MIB1 (marker of cell proliferation) showing two apoptotic cells (dark) and one MIB1-positive cell (blue), on the surface of the same alveolar wall (original magnification 160×). b) Note alveolar cell in proliferation close (blue) to apoptotic pneumocyte (dark) (Original magnification 160×).