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Table 2 Bland-Altman analysis of the differences in GL, EF50 and Cdyn.

From: Invasive versus noninvasive measurement of allergic and cholinergic airway responsiveness in mice

  

Early AR

Cholinergic AR

Group

Parameters

Mean ± SD

(95% CI)

Upper limit (95% CI)

Lower limit (95% CI)

Mean ± SD

(95% CI)

Upper limit (95% CI)

Lower limit (95% CI)

Allergic

EF50 vs. GL

-27.6 ± 17.8

(-42.6/-12.7)

8.0 (-17.8/33.9)

-63.3 (-89.2/-37.5)

-0.7 ± 0.7

(-1.3/0.1)

0.7 (-0.3/1.8)

-2.1 (-3.2/-1.1)

 

GL vs. Cdyn

13.3 ± 21.9

(-5/31.7)

57.1 (25.4/88.8)

-30.5 (-62.2/1.2)

0 ± 0.2

(-0.2/0.2)

0.4 (0.1/0.7)

-0.4 (-0.7/-0.1)

 

EF50 vs. Cdyn

-14.3 ± 29.5

(-39/10.3)

44.7 (2/87.4)

-73.3 (-116/-30.6)

-0.7 ± 0.9

(-1.4/0)

1 (-0.2/2.3)

-2.5 (-3.7/-1.2)

Control

EF50 vs. GL

-2.4 ± 9.5

(-10.4/5.5)

16.6 (2.8/30.5)

-21.5 (-35.3/-7.7)

-2.9 ± 3.3

(-5.7/-0.2)

3.7 (-1.1/8.5)

-9.5 (-14.3/-4.7)

 

GL vs. Cdyn

-3.7 ± 10.4

(-12.2/5.1)

17.2 (2.1 to 32.3)

-24.6 (-39.7/-9.4)

1.4 ± 1.8

(-0.2/2.9)

5 (2.4/7.7)

-2.3 (-4.9/0.4)

 

EF50 vs. Cdyn

-6.1 ± 9.1

(-13.8/-1.5)

12.2 (-1.1/25.4)

-24.4 (-37.6/-11.2)

-1.5 ± 3.5

(-4.5/1.4)

5.5 (0.4/10.7)

-8.6 (-13.8/-3.5)

  1. Differences in simultaneous invasive measurements of GL, EF50 and Cdyn for allergic and control mice during EAR and cholinergic AR. Values are means ± SD (95 % confidence intervals (CI) in brackets) for 8 animals per group. The upper and lower limits of agreement (means ± 2 SD) as well as the corresponding 95 % CI intervals (in brackets) are shown. Values for the EAR represent the % change from baseline, whereas the values for cholinergic AR show the absolute PD50 values in μg MCh.