Figure 1
From: Invasive versus noninvasive measurement of allergic and cholinergic airway responsiveness in mice
Early airway responsiveness. Invasive vs. noninvasive assessment of early airway responsiveness (EAR) to aerosolized Aspergillus fumigatus 2 %. Allergic (black columns) and control mice (white columns) were separated into groups of invasively and noninvasively monitored animals. The allergic mice showed significant reductions in simultaneously measured GL, Cdyn and EF50an (an: anesthetized), compared with control animals. Noninvasive determination of EF50con (con: conscious) elicited significant decreases in EF50 to inhaled A. fumigatus compared with control animals. EAR was expressed as % change from corresponding baseline values, which were taken as 0 %. Values are means ± SE, n = 8 per group, *p < 0.01 vs. control.