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Table 2 Protein recovered from the lungs

From: Therapeutic lung lavages in children and adults

Patients

concentration of protein (μg/ml)

concentration of protein (μg/ml and kg body weight)

amount of protein (mg)

amount of protein (mg/kg body weight)

 

BAL

half lung lavages

BAL

half lung lavages

BAL

half lung lavages

BAL

half lung lavages

PAP ped. (J01)

233 (195/285.1)

131 (107.5/163)

27.4

15.4 (12.6/19.2)

7.7 (7/10)

370 (287/405)

0.9

44 (34/48)

PAP ped. (J02)

306 (206.5/1149)

1010 (664/1199)

21.1

69.7 (45.8/82.7)

57 (39/134)

3214 (2262/4826)

3.9

222 (156/333)

PAP ped. (J03)

1034

2975

229.8

661

20.2

922

4.4

205

PAP ped. (J04)

352

269

81.9

62.6

5.1

223

1.2

52

median (25/75 percentile)

307 (207/1149)

236 (130/1010)

220 (147/252)§

29.7 (16.4/127)

11.7 (8/42)

545.8 (347/2618)

3 (1/4)

68.7 (43.6/329.3)

PAP adult (A01)

1490

924

21.3

13.2

226.7

12828

3.24

186

PAP adult (A02)

322

274

4.60

3.9

54.1

1766

0.77

26

PAP adult (A03)

135

199

1.92

2.8

21.4

3488

0.31

50

PAP adult (A04)

no data

569

no data

8.1

no data

15374

no data

220

PAP adult (A05)#

no data

161.5

no data

2

no data

3563

no data

45

PAP adult (A06)#

no data

1090

no data

13.6

no data

18820

no data

235

median (25/75 percentile)

846 (228/1491)

422 (180/1007)

4.6

5.8 (2.5/13.7)*

130 (38/227)$

5650 (1034/16850)ns

0.8

77 (14.1/229.8)ns

Cholesterol-Pneumonitis (L01)

136.2

157

10.5

16.8

1.7

124

0.13

9.5

control (C01)

47

n.a.

3.58

n.a.

0.6

n.a.

0.05

n.a.

control (C02)

58

n.a.

2.88

n.a.

2.7

n.a.

0.14

n.a.

control (C03)

77

n.a.

4.82

n.a.

1.7

n.a.

0.11

n.a.

control (C04)

82

n.a.

7.41

n.a.

1.4

n.a.

0.13

n.a.

control (C05)

47

n.a.

4.30

n.a.

1.0

n.a.

0.09

n.a.

control (C06)

85

n.a.

9.96

n.a.

1.8

n.a.

0.21

n.a.

control (C07)

97

n.a.

13.90

n.a.

1.2

n.a.

0.17

n.a.

control (C08)

77

n.a.

7.71

n.a.

1.1

n.a.

0.11

n.a.

control (C09)

65

n.a.

5.92

n.a.

1.1

n.a.

0.10

n.a.

control (C10)

49

n.a.

1.36

n.a.

3.2

n.a.

0.09

n.a.

median (25/75 percentile)

71 (48.2/83)

 

5.4 (3.2/8.8)

 

1.3 (1/2.3)§§§§

 

0.09

 
  1. n.a. = not applicable. only diagnostic bronchoalveolar lavage. i.e. 4 ml/kg in 4 fractions; LTX = lung transplantation; data are presented as median (25/75 percentile); y = years; # = only every second portion available. total protein calculated; BAL = bronchoalveolar lavage; f = female; m = male. Two groups were compared by Mann-Whitney-test: ns: not significant,*: p < 0.05, **: p < 0.01, ***: p < 0.001 indicate differences between pediatric and adult PAP All three groups (PAP ped, PAP adult and controls) were compared by Friedmann (ANOVA), followed by Dunn's post-hoc-test: +: p < 0.05, ++: p < 0.01, +++: p < 0.001 indicate differences between pediatric PAP and adult PAP. §: p < 0.05, §§:p < 0.01, §§§: p < 0.001 indicate differences between pediatric PAP and controls. $: p < 0.05, $$: p < 0.01, $$$: p < 0.001 indicate differences between adult PAP and control
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Respiratory Research

ISSN: 1465-993X

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