Figure 2
From: Isolation of human β-defensin-4 in lung tissue and its increase in lower respiratory tract infection
Immunohistochemical study of hBD-4 expression in the human lung. For each pair of images, the upper panels (A1, B1, and C1) are the results of the immunohistochemical study of the lung tissue obtained from a 38-year-old female with pulmonary mucormycosis, and the lower panels (A2, B2, and C2) are those obtained from a 70-year-old male with bullae. Immunoreactive cells are present around the bronchial surface (A1, A2) and bronchiolar surface (B1, B2). hBD-4 immunoreactivity is not detected in alveolar epithelial cells (C1 and C2). No immunoreactivity is detected in tissues following preadsorption of antiserum with 1 μg/ml hBD-4 peptide (D). The bar represents a length of 50 μm in all panels.