Figure 4From: Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migrationEffect of inhaled tolafentrine on the degree of muscularization and on the medial wall thickness of small pulmonary arteries. Immunohistochemical analysis of lung sections originating from saline (Control), monocrotaline (MCT[42d]) and monocrotaline plus tolafentrine (MCT[42d]/Tola) treated animals. Staining was undertaken for von Willebrand-factor (brown; endothelial cells) and alpha smooth muscle actin (purple; smooth muscel cells) as well as elastin. Scale bar: 20 μm.Back to article page