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Figure 2 | Respiratory Research

Figure 2

From: Prolastin, a pharmaceutical preparation of purified human α1-antitrypsin, blocks endotoxin-mediated cytokine release

Figure 2

Comparisons of the effects of native (nAAT), polymeric (pAAT) and Prolastin on lipopolysaccharide – stimulated TNFα (A) and IL-β (B) production by human blood monocytes isolated from four healthy donors. Isolated blood monocytes were treated with LPS (10 ng/ml) alone or together with 0.5 mg/ml nAAT, pAAT or Prolastin for 18 h. TNFα and IL-1β levels were measured by ELISA. Each bar represent the mean ± S.E. *** p < 0.001.

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