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Table 1 Subject characteristics§

From: Liquid chromatography/mass spectrometry analysis of exhaled leukotriene B4 in asthmatic children

 

Healthy children

Atopic nonasthmatic children

Steroid-naïve atopic asthmatic children

Steroid-treated atopic asthmatic children

n

15

20

25

22

Sex, F/M

8/7

9/11

12/13

10/12

Age, yr

10 ± 1

9 ± 1

10 ± 1

10 ± 1

FEV1, % pred

101.5 ± 1.8

100.8 ± 2.3

96.1 ± 1.4

97.5 ± 2.3

FVC, % pred

102.7 ± 2.8

103.2 ± 2.5

100.4 ± 2.3

101.5 ± 2.7

FEV1/FVC, %

99.8 ± 1.5

97.5 ± 2.6

87.1 ± 2.3*

85.8 ± 2.5*

FEF25–75%

104.0 ± 3.8

101.8 ± 4.1

68.2 ± 3.9**

83.7 ± 4.5*

  1. § Data are expressed as numbers or mean ± SEM.
  2. * P < 0.05 and ** P < 0.01 compared with healthy children. Steroid-treated asthmatic children were receiving either 100 μg/day or 200 μg/day of inhaled fluticasone at a constant dose for at least 8 weeks.