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Table 2 The thickness of various laminin chains in SEBM (μm)

From: Uncoordinated production of Laminin-5 chains in airways epithelium of allergic asthmatics

Laminin chain Healthy controls Allergic asthma Non-allergic asthma
α1-chain No staining Patchy, weak staining No staining
α2-chain 1.94 (1.70–2.20) 2.83 (2.50–3.30)**, ‡‡‡ 2.19 (1.8–2.90)
α3-chain 2.46 (1.80–3.10) 3.77 (3.30–4.40)***, ‡‡‡ 2.61 (2.20–3.10)
α4-chain No staining No staining No staining
α5-chain 2.31 (1.90–2.50) 4.10 (3.30–4.60)***, ‡‡‡ 2.86 (2.40–3.50) **
β1-chain 2.13 (1.60–2.80) 4.84 (4.10–5.50)***, ‡‡‡ 3.29 (3.10–3.80) ***
β2-chain 1.93 (1.60–2.60) 2.34 (2.10–2.800)*, ‡‡ 2.04 (1.80–2.300)
γ1-chain 2.47 (1.90–3.00) 4.86 (4.20–5.40) ***, ‡‡‡ 3.49 (2.90–3.90) ***
γ2-chain 2.03 (1.70–2.40) 2.96 (2.60–3.50)**, ‡‡‡ 2.36 (2.00–2.80)
  1. Results are given as medians and interquartile ranges. Differences between groups were calculated by the Mann-Whitney non-parametric test and statistical differences shown in the table. **, *** indicate p < 0.01 and p < 0.001, respectively, in the comparison between either of the two asthma groups with the results of the healthy controls. ‡, ‡‡, ‡‡‡ indicate p < 0.05, <0.01 and 0.001, respectively, in the comparison between the two asthma groups.