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Table 2 Hydroxyproline content (mg/g of dry tissue) in lung homogenate from p47phox +/+ WT and p47phox -/- KO mice, at day 14 after intranasal administration of bleomycin (BLM, 0.1 mg/mouse) or saline vehicle (Control, NaCl 0.9%). Results are presented as mean ± SEM. WT: wild-type; KO: knockout; ** : P < 0.01 for WT mice compared with KO mice. n = 3–6.

From: The absence of reactive oxygen species production protects mice against bleomycin-induced pulmonary fibrosis

Strain

Control

BLM

p47phox +/+ [WT]

1.20 ± 0.26

1.74 ± 0.10**

p47phox -/- [KO]

1.29 ± 0.24

1.04 ± 0.10