Table 4 TNF-α (A), IL-4 (B) and IL-5 (C) concentrations in BAL fluid recovered from male Balb/c mice following drug treatment. Cytokine concentrations were measured using a Biolplex ELISA system. Each study group contained n = 8 mice.

A

19.9 ± 5.3

10.7 ± 0.5

18.2 ± 0.58

B

43.2 ± 5.1 a

123.6 ± 66.3 a

1077.1 ± 273.5 a

C

41.6 ± 3.6

120.3 ± 5.3

1339.7 ± 120.5

D

22.9 ± 4.6 c

50.7 ± 2.4 c

591.9 ± 108.2 c

E

47.1 ± 5.0

129.4 ± 11.0

1652.9 ± 174.1

F

41.6 ± 6.8

112.8 ± 11.9

1592.5 ± 301.4

G

46.5 ± 6.5

139.3 ± 40.7

1290.3 ± 218.4

H

38.3 ± 7.2

110.1 ± 18.0

1007.6 ± 194.5

I

39.1 ± 7.6

104.8 ± 27.5

1634.9 ± 367.7

J

16.7 ± 3.6 c

15.8 ± 2.1 b

227.9 ± 45.0 b