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Figure 1 | Respiratory Research

Figure 1

From: The effect of selective phosphodiesterase inhibitors, alone and in combination, on a murine model of allergic asthma

Figure 1

Total leukocyte (A) and eosinophil (B) numbers in BAL fluid recovered from male Balb/c mice following drug treatment. Group A was non-OVA challenged mice orally injected with saline. Groups B to J were OVA challenged mice orally injected with either saline (Group B) or PDE compound (3 mg/kg). Group C received cilostazol. Group D received RO 20-1724. Group E received sildenafil. Group F received cilostazol + RO 20-1724. Group G received cilostazol + sildenafil. Group H received RO 20-1724 + sildenafil. Group I received cilostazol + RO 20-1724 + sildenafil. Group J received Dexamethasone. Each study group contained n = 8 mice. + p < 0.001 compared to non OVA challenged mice (Group A), b p < 0.01 compared to OVA challenged mice orally gavaged with saline, c p < 0.05 compared to OVA challenged mice orally gavaged with saline

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