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Figure 1 | Respiratory Research

Figure 1

From: Models of chronic obstructive pulmonary disease

Figure 1

Potential pathogenetic mechanisms involved in COPD Exogenous inhaled noxious stimuli such as tobacco smoke, noxious gases or indoor air pollution and genetic factors are proposed to be the major factors related to the pathogenesis of COPD. These factors may influence protease activity and may also lead to an imbalance between pro-inflammatory and anti-inflammatory mediators.

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