Figure 1

Mean change from baseline in morning peak expiratory flow (PEF) in patients treated with placebo or various doses of budesonide. A significant dose-response effect is seen. However, it should be noted that the difference between placebo and low-dose budesonide is greater than the difference between low-dose budesonide and high-dose budesonide and that there is no statistically significant difference between the various doses of budesonide. Reproduced from reference 33 with permission.