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Table 4 Adverse Events Score (centimeters, mean ± SD) using Visual Analog Scale (1–10)*

From: Safety assessment of inhaled xylitol in mice and healthy volunteers

Symptom Baseline VAS score Change Post-saline Change Post-10 ml xylitol Change on day 5 follow-up
Chest tightness 0 0 0.2 ± 0.4 0
Shortness of breath 0 0 0 0
Cough 0.25 ± 0.8 0.05 ± 0.15 0 0
Headache 0 0 0.2 ± 0.6 0
Chills 0 0 0 0
Muscle soreness 0.2 ± 0.6 0 0 -0.2 ± 0.6
Phlegm 0.2 ± 0.6 0 0.25 ± 0.4 0
Nausea 0 0 0 0
Stuffy/Runny Nose 0 0 0.65 ± 0.9† 0
Sneezing 0 0 0 0
Fatigue 0.1 ± 0.3 0 -0.1 ± 0.3 0
  1. *P-values of all changes from baseline are >0.05 except for stuffy nose after xylitol expsoure.
  2. † P-value = 0.03.