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Table 2 BAL cell differential in wild-type and iNOS knockout mice after 72 h exposure to 21%, 60%, and >95% O2*

From: Proinflammatory role of inducible nitric oxide synthase in acute hyperoxic lung injury

   alveolar macrophages (%) neutrophils (%) lymphocytes (%)
wild-type mice 21% O2 98.8 ± 0.5 0.0 ± 0.0 1.2 ± 0.5
  60% O2 97.7 ± 1.0 0.3 ± 0.2 2.0 ± 1.0
  >95% O2 86.2 ± 1.8#* 4.6 ± 1.0#* 9.2 ± 0.9#*
iNOS knockout mice 21% O2 99.0 ± 0.4 0.7 ± 0.2 0.3 ± 0.2
  60% O2 98.9 ± 0.5 0.4 ± 0.3 0.7 ± 0.4
  >95% O2 85.1 ± 2.0#* 4.9 ± 1.3#* 10.0 ± 1.2#*
  1. *Each value represents mean ± SEM, n = 7.
  2. #p < 0.05 vs. normoxia; *p < 0.05 vs. 60% O2