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Table 2 BAL cell differential in wild-type and iNOS knockout mice after 72 h exposure to 21%, 60%, and >95% O2*

From: Proinflammatory role of inducible nitric oxide synthase in acute hyperoxic lung injury

  

alveolar macrophages (%)

neutrophils (%)

lymphocytes (%)

wild-type mice

21% O2

98.8 ± 0.5

0.0 ± 0.0

1.2 ± 0.5

 

60% O2

97.7 ± 1.0

0.3 ± 0.2

2.0 ± 1.0

 

>95% O2

86.2 ± 1.8#*

4.6 ± 1.0#*

9.2 ± 0.9#*

iNOS knockout mice

21% O2

99.0 ± 0.4

0.7 ± 0.2

0.3 ± 0.2

 

60% O2

98.9 ± 0.5

0.4 ± 0.3

0.7 ± 0.4

 

>95% O2

85.1 ± 2.0#*

4.9 ± 1.3#*

10.0 ± 1.2#*

  1. *Each value represents mean ± SEM, n = 7.
  2. #p < 0.05 vs. normoxia; *p < 0.05 vs. 60% O2
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Respiratory Research

ISSN: 1465-993X

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