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Table 2 Phenotypic characteristics of γδ T cells before and after 8 days of culture with cytosolic extract from P. aeruginosa (PA)

From: γδ T lymphocytes from cystic fibrosis patients and healthy donors are high TNF-α and IFN-γ-producers in response to Pseudomonas aeruginosa

  Vγ9 day 0 Vγ9 day 8 Vδ2 day 0 Vδ2 day 8 CD4 day 0 CD4 day 8 CD8 day 0 CD8 day 8
Controls 84.71 ± 3.12** 92.85 ± 1.70 77.67 ± 3.8* 89.46 ± 3.43 2.03 ± 0.93 0.76 ± 0.65 11.92 ± 2.55 10.13 ± 1.91
CFw 89.83 ± 2.78* 94.75 ± 2.06 84.65 ± 3.89* 92.39 ± 3.23 0.49 ± 0.26 0.27 ± 0.18 9.21 ± 1.17 10.13 ± 1.91
CFp 92.52 ± 1.40** 96.82 ± 1.14 85.90 ± 3.88** 94.44 ± 2.72 0.78 ± 0.37 0.54 ± 0.31 9.48 ± 1.80 9.84 ± 2.69
CFn 82.80 ± 8.8 87.45 ± 7.98 79.46 ± 10.32 87.32 ± 8.64 0.1 ± 0.01 0.1 ± 0.01 8.41 ± 1.53 11.28 ± 3.42
  1. Results are expressed as the percentage of positive cells (mean ± s.e.m.) in the γδ T subpopulation. CFw (cystic fibrosis patients, n = 14), CFp (cystic fibrosis patients infected by PA, n = 8), CFn (cystic fibrosis patients without PA, n = 4). Means comparison between paired samples (days 0 and 8) were made by the Student's t test: *Significantly lower than the value at day 8: p < 0.01 **Significantly lower than the value at day 8: p < 0.05