γδ T lymphocytes from cystic fibrosis patients and healthy donors are high TNF-α and IFN-γ-producers in response to Pseudomonas aeruginosa

Table 1 Characteristics of cystic fibrosis patients included in the study

Patients	Age	Mutations	History of infections	PA culture	Shwachman score	Additional Data
MGV	15	ΔF508/ΔF508	PA chronic colonization	Pos	95
MGP	14	ΔF508/ΔF508	PA chronic colonization, occasional SA	Pos	76
AAS	17	ΔF508/?	PA chronic colonization	Pos	60
AGH	15	ΔF508/?	PA chronic colonization	Pos	80
MCC	14	ΔF508/?	SA and PA chronic colonization	Pos	65	DMID
LGS	5	ΔF508/ΔF508	PA chronic colonization	Pos	85
EML	29	R347H/ΔF508	PA chronic colonization	Pos	55
DNP	12	ΔF508/2789+ 563A	PA chronic colonization	Pos	95
YML	23	R347H/ΔF508	PA chronic colonization	Pos	55
MVG	8	ΔF508/ΔF508	occasional SA	Neg	90
VMM	8	ΔF508/G542X	#	Neg	85
ASA	7	ΔF508/L206W	SA chronic colonization, occasional HI	Neg	95
GCF	10	ΔF508/ΔF508	occasional SA	Neg	85
MSP	21	ΔF508/?	* PA chronic colonization	*	71	DMID

PA: Pseudomonas aeruginosa, SA: Staphylococcus aureus, HI: Haemophilus influenzae. Pos: sputum culture positive for PA, Neg: sputum culture negative for PA, DMID:Diabetes mellitus insulin-dependent. # PA colonization until 2 years before blood extraction, negative from this date until now * PA negative only for one year, blood extraction was made during this year Schwachman score rates severity based on history, physical examination and chest roentgenogram

ISSN: 1465-993X