Skip to main content
Figure 2 | Respiratory Research

Figure 2

From: Growth factor signaling in lung morphogenetic centers: automaticity, stereotypy and symmetry

Figure 2

Potential interactions between Fibroblast Growth Factor7 (FGF7) and Fibroblast Growth Factor10 (FGF10) and cognate FGF receptors (FGFR1b and FGFR2b). FGF10 can activate both FGFR1b and FGFR2b. On the other hand, FGF7 only activates FGFR2b. Activation of FGFR1b by FGF10 may be responsible for chemotaxis, while epithelial cell proliferation and differentiation is mediated by both FGF10 and FGF7 activation of FGFR2b. This is mediated downstream by activation of specific target genes.

Back to article page