Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization

Table 1 C57BL/6 mice showed significantly heightened BAL protein levels and inflammatory changes in the BAL phospholipid profile in comparison with Balb/c mice following allergic sensitization and challenge with Af.

Protein and phospholipid content were analyzed from the large aggregate (LA) and the small aggregate (SA) surfactant fractions of naïve and sensitized mice as described. Data are expressed as amount of protein or phospholipid (micrograms) per mouse lung. Mean ± SEM of n = 16–22 mice per group were calculated after deriving the average of the results from two independent experiments. *p < 0.05 Sensitized vs Naive; #p < 0.05 C57BL/6 vs Balb/c.

ISSN: 1465-993X