Figure 4

Time and concentration dependent effect of platelet lysate on fibroblast mediated collagen gel contraction. Various dilutions of platelet lysate were mixed together with fibroblasts in collagen gels. After gelation, the gels were released and the area of the floating gels was measured after 2 (solid line) and 4 (dotted line) days. Vertical axis: gel area expressed as percentage of original gel size. Horizontal axis: dilutions of platelet lysate, control contain no lysate. Data presented as mean of triplicate. ± SEM were less than 1%. P < 0.001: HFL1 vs. platelet lysate at all data points.