Skip to main content

Advertisement

Table 3 Comparison of Inflammatory biomarkers secreted by monocytes isolated from individuals with and without severe PiZZ AAT-deficiency

From: Circulating monocytes from healthy individuals and COPD patients

Measured Biomarker PiMM   PiZZ   Significance
  Mean SD Mean SD P
MMP-9 (ng/ml) 5 1.9 4.4 1 0.3
MCP-1 (pg/ml) 498 124 348 95 0.06
ICAM-1(ng/ml) 130 13 145 14 0.45
TNF-α (pg/ml) 12.8 9 5.7 2.5 0.029
MIF (pg/ml) 1315 192 1179 264 0.34
IL-6 (pg/ml) 18 1.9 18.4 3 0.414
IL-1β (pg/ml) 5.9 3 3 0.9 0.14
IL-8 (pg/ml) 2.2 0.4 2.5 0.47 0.843