Moxifloxacin treatment results in a reduced infiltrate of TNF-α-expressing cells. Moxifloxacin- and saline-treated mice were infected intranasally with viable P. aeruginosa for 6 h. (A) Hematoxylin and eosin staining. (B) TNF-α is shown by immunohistochemistry. Scale bar represents 200 μm. Samples from three different animals per group are shown. (C) Quantification of TNF-α staining in 4 slides per mouse. Bar indicates significant difference of p < 0.05.