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Table 2 Plasma concentration of MMPs, MMP-9/TIMP-1 complex and C-reactive protein

From: FEV1 inversely correlates with metalloproteinases 1, 7, 9 and CRP in COPD by biomass smoke exposure

 

Control

BE

TS

p

Molecule

MMP-1 (ng/mL)

1.62 ± 0.71

4.24 ± 2.17*

3.86 ± 2.71*

0.01

MMP-7 (ng/mL)

1.79 ± 0.26

2.63 ± 1.12*

2.87 ± 1.26*

0.01

MMP-9 (ng/mL)

4.46 ± 0.65

7.97 ± 3.53*

9.07 ± 2.84*

0.01

MMP-9/TIMP-1 (pg/mL)

0.18 ± 0.17

0.25 ± 0.18

0.32 ± 0.21*

0.05

C-reactive protein (ng/mL)

12.34 ± 6.04

32.89 ± 21.29*

35.49 ± 21.19*

0.05

  1. BE: Biomass exposure; TS: Tobacco smoking.
  2. Data are express as means ± SD. *ANOVA-Tukey test compared with Controls.
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Respiratory Research

ISSN: 1465-993X

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