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Table 1 Clinical characteristics of COPD and NS healthy women (control)

From: FEV1 inversely correlates with metalloproteinases 1, 7, 9 and CRP in COPD by biomass smoke exposure

  Control n = 40 BE n = 40 TS n = 40 p
Characteristics
Age (years) 65 ± 10 72 ± 8§ 69 ± 9 0.01 vs Ctrl
Height (cm) 158 ± 6 147 ± 7§ 159 ± 10 0.01 vs TS
0.02 vs TS
Weight (Kg) 65.9 ± 9 62 ± 11 69 ± 9§ 0.05 vs Ctrl
BMI (Kg/m2) 27 ± 8 29 ± 5 26 ± 3§ 0.01 vs BE
Exposure and physiological characteristics
Tobacco index (Pack/yr) - - 50 ± 30  
Biomass index (Hrs/year of exposure) - 230 ± 132 -  
FEV1 (% predicted) 107.8 ± 8.7 62.1 ± 25.6§ 49.5 ± 23.9§ 0.01 vs Ctrl
0.03 BE vs TS
FVC (% predicted) 109 ± 9 78 ± 19§ 82 ± 14§ 0.01 vs Ctrl
FEV1/FVC ratio 91 ± 9.5 53 ± 16§ 56 ± 15§ 0.01 vs Ctrl
Bronchodilator response (FEV1; %) - 9.54 ± 17 9.14 ± 8 0.883**
PaO2 (mmHg) - 53 ± 7 59 ± 10 0.056**
PaCO2 (mmHg) - 34 ± 4 32 ± 5 0.136**
6MWT (m) - 274 ± 155 327 ± 142 0.075**
SaO2 (%) - 88 ± 5 91 ± 5 0.039**
Chronic respiratory questionnaire
Dyspnea - 21 ± 10 17 ± 8 0.098**
Fatigue - 19 ± 5 20 ± 5 0.711**
Master - 37 ± 7 36 ± 9 0.570***
Control - 22 ± 4 22 ± 5 0.988**
Total score - 99 ± 15 95 ± 17 0.283**
GOLD stage     
I - 8 (20) 8 (20) 0.075*
II - 25 (63) 15 (38)
III - 6 (15) 12 (30)
IV - 1 (2.) 5 (12)
Exacerbation rate/yr (min-max) - 1.27 (1-3) 1.38 (1-3) 0.495**
  1. Data are presented as mean ± SD unless otherwise indicated. Ctrl = Control; BE = biomass exposure; TS: tobacco smoking; BMI: biomass mass index; FEV1: forced expiratory volume in one second; FVC: forced vital capacity;% predicted: percentage of the predicted value. For GOLD stage figures are presented as number (%).
  2. Statistical tests: §ANOVA-Tukey test; *X2 test; **Student-T test; ***Welch test. All comparisons with Ctrl and TS were against BE after Bonferroni adjustments.