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Table 1 Hemodynamic data

From: N-acetylcysteine improves established monocrotaline-induced pulmonary hypertension in rats

 

Cont

MCT

MCT + NAC

RVSP (mmHg)

38.4 ± 6.0

102.6 ± 12.1*

93.1 ± 24.7*

mPAP (mmHg)

14.1 ± 1.6

34.6 ± 5.8*

36.6 ± 12.2*

CO (mL.min -1 )

116.6 ± 14.6

45.1 ± 4.8*

80.4 ± 21.2*#

TPR (mmHg.min.mL -1 )

0.12 ± 0.02

0.71 ± 0.14*

0.50 ± 0.17*#

RV/LV + S

0.28 ± 0.04

0.67 ± 0.08**

0.49 ± 0.07**##

  1. NAC improves MCT-induced cardiac dysfunction without effect on right ventricle and pulmonary artery pressure. Data are represented as mean ± SD. RVSP: Right ventricular systolic pressure, mPAP: mean pulmonary arterial pressure, CO: cadiac output, TPR: total pulmonary resistances. *p < 0.05 vs cont, **p < 0.001 vs cont, #p < 0.05 vs MCT, ##p < 0.001 vs MCT (n = 8–14).
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Respiratory Research

ISSN: 1465-993X

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