Figure 3
From: N-acetylcysteine improves established monocrotaline-induced pulmonary hypertension in rats
NAC decreases cardiomyocytes hypertrophy and fibrosis in RV rats with PH. In the first part (A), representative image of cardiomyocytes in RV of control rat (1) MCT rats (2) and MCT rats treated with NAC from days 14 to day 28 after MCT exposure (3). In the second part (B), representative image of collagen (red stained) content in RV of control rat (1) MCT rats (2) and MCT rats treated with NAC from days 14 to day 28 after MCT exposure (3). All photomicrographs were taken at G20 magnification. 4: Bar graphs are summary data for cardiomyocyte area (n = 180 per group) and collagen area fraction (n = 60 per group), as mean ± SEM and *P < 0.05 vs cont (n = 180 per group).