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Table 4 Aspiration-related symptoms, and radiologic measurements stratified by history of GERD*

From: Impact of self-reported Gastroesophageal reflux disease in subjects from COPDGene cohort

 

GERD (n = 1,307)

No GERD (n=3,176)

Total (n=4,483)

P-value

History of Pneumonia (%)

58.1

43.9

48.1

<0.0001

Asthma (%)

28.8

20.0

22.6

<0.0001

Have a cough (%)

47.4

41.7

43.3

0.0004

Have wheezing (%)

69.8

55.5

59.7

<0.0001

CT calculated TLC, liters [mean (s.d.)]

5.9 (1.4)

6.0 (1.4)

6.0 (1.4)

0.003

Emphysema [mean (s.d.)]

11.9 (12.1)

11.3 (12.1)

11.5 (12.1)

0.20

Emphysema >20% (%)

23.9

22.9

23.2

0.12

% Gas trapping [mean (s.d.)]

35.9 (20.0)

35.4 (21.2)

35.5 (20.1)

0.40

Wall thickness in mm [mean (s.d.)]

62.4 (3.2)

62.4 (3.2)

62.4 (3.2)

0.90

Pi10

3.7 (0.1)

3.7 (0.1)

3.7 (0.1)

0.30

  1. *Means and standard deviations of the mean or percentages are presented; p-values represent t-test or chi-square comparison between groups.