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Table 3 Characteristics of index community-acquired pneumonia infection

From: Early versus later response to treatment in patients with community-acquired pneumonia: analysis of the REACH study

Characteristic, n (%)

Early responders n = 332

Later responders n = 253

Patients without Halm-based assessment of TCS n = 1454

Type of CAP

 CAP*

279 (84.0)

210 (83.0)

1118 (76.9)

 HCAP

24 (7.2)

20 (7.9)

201 (13.8)

 Immunocompromised/immunosuppressed

8 (2.4)

11 (4.3)

53 (3.6)

 Other

0

2 (0.6)

37 (2.5)

 Unknown

21 (6.3)

10 (4.0)

54 (3.7)

Radiographic findings suggestive of bacterial pneumonia

 Infiltrate

175 (52.7)

113 (44.7)

880 (60.5)

 Consolidation

183 (55.1)

167 (66.0)

597 (41.1)

 Pleural effusion

40 (12.0)

44 (17.4)

235 (16.2)

 Other

19 (5.7)

14 (5.5)

67 (4.6)

 Unknown

0

1 (0.4)

15 (1.0)

Signs of acute illness at diagnosis

 New or increased cough

258 (77.7)

202 (79.8)

1115 (76.7)

 Purulent sputum or change in sputum character

182 (54.8)

127 (50.2)

744 (51.2)

 Auscultatory findings consistent with pneumonia

253 (76.2)

184 (72.7)

1055 (72.6)

 Dyspnoea, tachypnoea or hypoxaemia

256 (77.1)

210 (83.0)

1025 (70.5)

 Fever or hypothermia

213 (64.2)

153 (60.5)

951 (65.4)

 White blood cell count > 10000 cells/mm3 or < 4500 cells/mm3

210 (63.3)

179 (70.8)

963 (66.2)

Prognosis based on severity indices

 PORT/PSI

65 (19.6)

77 (30.4)

212 (14.6)

   I/II

17 (26.2)

13 (16.9)

41 (19.3)

   III/IV

43 (66.2)

50 (64.9)

138 (65.1)

   V

5 (7.7)

14 (18.2)

33 (15.6)

 CURB-65

129 (38.9)

118 (46.6)

280 (19.3)

   0-1

49 (38.0)

23 (19.5)

82 (29.3)

   2

38 (29.5)

42 (35.6)

105 (37.5)

   3

16 (12.4)

23 (19.5)

61 (21.8)

   4

21 (16.3)

26 (22.0)

21 (7.5)

   5

2 (1.6)

3 (2.5)

3 (1.1)

   Unknown

3 (2.3)

1 (0.8)

8 (2.9)

  1. *Residence in private house or apartment only.
  2. Responses considered HCAP were all other residential statuses, with the exception of immunocompromised/immunosuppressed.
  3. The proportions are calculated with respect to the total number of patients in which this score was reported to have been used to assess clinical stability.
  4. CAP = community-acquired pneumonia; CURB-65 = Confusion, Urea nitrogen, Respiratory rate, Blood pressure, ≥ 65 years of age; HCAP = healthcare-associated pneumonia; PORT/PSI = Pneumonia Outcomes Research Team/Pneumonia Severity Index; SD = standard deviation; TCS = time to clinical stability.