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Table 1 Baseline characteristics and radiology

From: Clinical and computed tomographic predictors of chronic bronchitis in COPD: a cross sectional analysis of the COPDGene study

  Chronic bronchitis (CB+) n = 663 No chronic bronchitis (CB-) n = 2040 p
Demographics and symptoms    
Age (years) 61.8 ± 8.5 63.8 ± 8.5 <0.0001
Smoking history (pack years) 56.4 ± 26.8 50.7 ± 26.3 <0.0001
Current smokers (%) 59.2 37.4 <0.0001
Gender (%M) 64 55 <0.0001
Race (%C) 84 78 <0.0001
FEV1 (% predicted) 54.3 ± 20.7 60.1 ± 23.4 <0.0001
FVC (% predicted) 80.5 ± 19.9 84.0 ± 20.1 <0.0001
FEV1/FVC 0.51 ± 0.13 0.53 ± 0.14 <0.0001
6MWD (meters) 372 ± 118 392 ± 121 <0.0001
BMI (kg/m2) 27.3 ± 5.9 27.7 ± 5.8 0.144
BODE score 3.0 ± 2.0 2.3 ± 2.1 <0.0001
MMRC dyspnea 2.3 ± 1.4 1.6 ± 1.5 <0.0001
SGRQ score 48.0 ± 21.3 30.6 ± 21.8 <0.0001
Exposures and Medical History    
Gastroesophageal reflux (%) 33.8 28.6 0.010
Allergic nasal symptoms (%) 69.5 47.0 <0.0001
Allergic ocular symptoms (%) 51.0 37.9 <0.0001
History of asthma (%) 33.4 23.4 <0.0001
History of bronchitis (%) 66.0 49.8 <0.0001
Exposure to dusts (%) 64.7 47.4 <0.0001
Occupational exposures (%) 65.6 51.0 <0.0001
Exacerbations    
Total exac rate (no./pt/yr) 0.96 ± 1.46 0.52 ± 1.04 <0.0001
History of severe Exac (%) 24.2 15.2 <0.0001
Radiology    
% Emphysema (%) 11.4 ± 12.0 12.0 ± 12.6 0.347
% Gas trapping (%) 35.3 ± 21.2 36.3 ± 20.6 0.272
Mean segmental WA% (%) 63.0 ± 3.2 62.0 ± 3.1 <0.0001
Pi10 (mm) 3.72 ± 0.15 3.69 ± 0.14 <0.0001
Pi15 (mm) 5.24 ± 0.22 5.17 ± 0.20 <0.0001
  1. Definition of abbreviations: M = male, F = female, C = Caucasian, AA = African American, FEV1 = forced expiratory volume in 1 second, FVC = forced vital capacity, 6MWD = 6-minute walk distance, Exac = exacerbation, BMI = body mass index.