Table 4 Serum biomarkers
From: MMP-2 and TIMP-1 predict healing of WTC-lung injury in New York City firefighters
| Â | Analyte pg/mL | 75th percentile cutpiont | Controls | Resistant | OR (95% CI) | ||
|---|---|---|---|---|---|---|---|
| Â | Â | Â | Median (IQR) | Proportion | Median (IQR) | Proportion | Â |
Proteases | MMP-1 | 1239 | 689 (264–1210) | 27/111 | 549 (233–1013) | 14/77 | 0.691 (0.335-1.425) |
MMP-2 | 4949 | 2933 (1570.01-4608.25) | 22/111 | 3340 (2108.19-5682.13) | 27/77 | 2.185 (1.128-4.231) | |
MMP-3 | 13345 | 7494 (2940–13358) | 28/111 | 6906 (3457–11509) | 17/77 | 0.840 (0.422-1.671) | |
MMP-7 | 355 | 217 (100–333) | 25/111 | 237 (95–375) | 22/77 | 1.376 (0.707-2.-77) | |
MMP-8 | 157 | 10 (10–156) | 27/111 | 10 (10–116) | 16/77 | 0.816 (0.405-1.645) | |
MMP-9 | 62086 | 22559 (10596–40806) | 24/111 | 23003 (12043–64398) | 21/77 | 1.359 (0.692-2.670) | |
MMP-12 | 306 | 66 (18–306) | 28/111 | 55 (27–277) | 19/77 | 0.971 (0.496-1.902) | |
MMP-13 | 138 | 75 (10–133) | 26/111 | 71 (10–140) | 20/77 | 1.147 (0.585-2.248) | |
Anti-proteases | TIMP-1 | 155003 | 125491 (100396–151151) | 23/111 | 126292 (100483–164661) | 29/77 | 2.312 (1.206-4.430) |
TIMP-2 | 115905 | 102470 (89901–113738) | 23/111 | 103199 (88959–119820) | 22/77 | 1.530 (0.780-3.005) | |
TIMP-3 | 31922 | 7750 (7750–31922) | 29/111 | 7750 (7750–33680) | 21/77 | 1.060 (0.550-2.044) | |
|  | TIMP-4 | 1585 | 1242 (9288–1562) | 26/111 | 1342 (970-(1717) | 27/77 | 1.765 (0.929-3.354) |